Our new Very clear+ tissue clearing approach is the sole approach that delipidates samples with no transform in morphology and with minimal impact on structural integrity.
Megatome can be a vibrating microtome meant to portion a broad array of samples, from organoids and biopsy samples to expanded rodent brains and intact human organs. With high blade vibrating frequency and minimized blade deflection, Megatome permits large-throughput tissue sectioning with uniform floor profile, together with negligible tissue damage and information loss.
Antibodies may well acquire months to diffuse by only some millimeters of tissue, that has a steep labeling gradient from area to Main.
Megatome is created for precision: the blade vibrates at the next frequency and bigger amplitude vary than other microtomes, and encompasses a one of a kind deflection Command system.
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Our preformulated EasyIndex Answer raises and homogenize the refractive index of delipidated tissue samples, rendering them megatomi.com fully clear. This permits mild penetration to the sample and guarantees the acquisition of high-resolution, in-aim impression info.
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eFLASH is a quick tissue labeling technique that permits for uniform full-organ staining in 20 rounds of labeling.
The SmartSPIM gentle sheet microscope provides unparalleled resolution and acquisition pace through intact tissue volumes, whilst its modular style and design enables you to enhance and customize particular person elements.
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Leverage the Distinct+ tissue clearing strategy, coupled with eFLASH and patented stochastic electrotransport technologies, to speedily apparent and label full organs. Crucial highlights and characteristics involve:
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